Graphical abstract to explain the role of endothelial IGF-1 receptor mediating crosstalk with the gut wall to regulate microbiota in obese mouse.

The endothelium and the gut microbiota

Scientific illustration

Scientific illustration showing how IGF-1 receptor expression in mice mediates crosstalk with the gut wall to regulate microbiota in obesity. Illustration made in collaboration with Somersault 18:24 and published in Bouman Chen Z. and Kaur Malhi N. EMBO Reports. 2021.